Major has discontinued theophylline Sustained release tablet. Teva’s theophylline extended-release tablets have been temporarily unavailable for several years. Mylan, Rhodes and Endo Pharmaceuticals offer theophylline as a 24 hour extended release formulation.

Is theophylline no longer used?

While theophylline has been used to treat asthma since 1922, it has been favored and out of favor by physicians since then, and today, not as commonly used as it is used to be.

Why no longer use theophylline?

Oral theophylline has been used as a bronchodilator for chronic obstructive pulmonary disease (COPD) for decades, but Falling out of favor due to side effects from higher doses required to achieve any beneficial effectand advances in improving drug treatment.

Is there an alternative to theophylline?

Abstract: DoxofyllineUnlike theophylline, it contains a dioxane group at the 7th position, which has comparable efficacy to theophylline in the treatment of respiratory diseases, but is better tolerated and has a higher risk-benefit ratio.

What is the common name for theophylline?

If shortness of breath occurs suddenly, use your rapid inhaler as prescribed. Theophylline has the following different brand names: Theo 24, TheoElixophyllin, Aminophylline and Uniphyl.

Theophylline (mnemonic for USMLE)

21 related questions found

Which foods contain theophylline?

Theophylline is present in Black tea with a small amount of green coffee, cocoa cotyledons and dried yerba mate. Theophylline is synthesized on an industrial scale and is mainly used in pharmaceutical preparations.

Is theophylline bad for the kidneys?

However, older patients may be more sensitive to the effects of theophylline than younger patients and are more likely to suffer from kidneyliver, heart, or lung problems, which may require caution and dosage adjustment in patients receiving theophylline.

What happens when you stop taking theophylline?

« If you suddenly stop taking theophylline, your Asthma symptoms may recur, which can lead to a potentially fatal asthma attack. « 

Is theophylline still used for COPD?

For more than 70 years, theophylline has been used to treat chronic obstructive airway disease, including chronic obstructive pulmonary disease (COPD). It is still widely used around the worldbecause it is not expensive.

When should you take theophylline?

Take theophylline exactly as directed. Don’t eat more or less, or more often than your doctor prescribes. Take this medication with a full glass of water on an empty stomach, At least 1 hour before meals or 2 hours after meals.

What are the side effects of theophylline?

Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist right away.

Can you overdose on theophylline?

Data from this cohort study suggest that theophylline is a highly toxic drug that, when taken in overdose, May cause injury or death. There are three distinct modes of intoxication, namely acute intoxication, chronic overdose and acute treatment intoxication.

What are the indications for theophylline?

Theophylline for treatment Symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseasessuch as emphysema and chronic bronchitis.

Is it okay to drink coffee with theophylline?

theophylline caffeine

Avoid caffeinated beverages or foods, such as coffee, tea, cola and chocolate. If you use both medicines at the same time, you may need a dose adjustment or special tests.

Is theophylline used for Covid 19?

Introduction: Phosphodiesterase inhibitors theophylline and pentoxifylline have Anti-inflammatory properties This may make them useful for COVID-19 pneumonia.

What Causes Low Theophylline Levels?

The increased clearance of theophylline and the resulting low levels are caused by eat barbecue; youth (ages 1-16); low-carb, high-protein diets; acidosis; and smoking cigarettes and marijuana.

What is COPD Theophylline?

Theophylline is a Bronchodilator, which are medicines that make breathing easier. Your healthcare provider may prescribe theophylline as a tablet or liquid. This medication can relieve symptoms of asthma, emphysema, or other lung diseases.

Do you need a prescription for theophylline?

Theophylline is prescription. It is available as an oral solution, extended-release tablets, and extended-release capsules. It is also available as an intravenous (IV) injection only by a healthcare provider. Theophylline tablets are only available as generic drugs.

Does theophylline have anti-inflammatory properties?

Theophylline does have Anti-inflammatory effect Cytokine mainly produced by mononuclear phagocytes.

What are the signs and symptoms of theophylline poisoning?

Neurological signs include tremor (most common), restlessness, agitation, and altered mental status. Sustained seizures may occur at serum levels > 25 mcg/mL. Gastrointestinal manifestations are nausea, vomiting, abdominal cramps, and diarrhea.

Does theophylline cause weight loss?

Common side effects of Theo-24 include mild nausea, loss of appetite, stomach pain, diarrhea, upset stomach, weight loss, restlessness, tremors, sleep problems (insomnia), headache, dizziness, lightheadedness, sweating, restlessness, nervousness or irritability.

Does theophylline increase heart rate?

In healthy subjects, Theophylline increases heart rate and systolic blood pressure, but this effect was not significant compared with placebo (Table 4).

Does theophylline raise blood pressure?

Theophylline increases mean arterial pressure by 7% Neither metoprolol nor propranolol attenuated. Theophylline does not change the heart rate.

Does theophylline raise blood sugar?

During the most active phase of glucose counterregulation, Theophylline group had a greater increase in blood sugar (P = .003 in diabetic patients, P = .03 in healthy subjects).

Does green tea contain theophylline?

Green tea extract contains PolyphenolsThese include the most active type, epigallocatechin gallate. Green tea and oolong tea have the highest polyphenol content. … other important components of tea include caffeine, theobromine, and theophylline.