Zemplar™ (Paricalcitol Injection) is a synthetically manufactured vitamin D analog.It is a sterile, clear, colorless aqueous solution for vein injection.

What is intravenous paricalcitol?

illustrate.Paricalcitol Injection For the treatment and prevention of hyperparathyroidism in patients with chronic kidney disease who is on dialysis. Hyperparathyroidism is caused by excessive production of parathyroid hormone (PTH) by the parathyroid glands located in the neck.

How to give zemplar?

Manage ZEMPLAR Intravenous via hemodialysis vascular access Any time during dialysis. If an access port is not available, ZEMPLAR can be administered intravenously. Visually inspect ZEMPLAR prior to administration; the solution should be clear and colorless.

Is paricalcitol the same as calcitriol?

Conclusions: Paricalcitol treatment reduced PTH concentrations more rapidly, had fewer episodes of persistent hypercalcemia, and increased Ca x P production compared with calcitriol treatment.

Why is zemplar given during dialysis?

Vitamin D is important for the absorption of calcium from the stomach and the function of calcium in the body.Zampra is Used to treat or prevent overactive parathyroid glands (hyperparathyroidism) in chronic kidney disease patients undergoing dialysis.

Treatment of hyperparathyroidism in patients with chronic kidney disease

42 related questions found

What are the side effects of Zemplar?

Tell your doctor right away if you have any serious side effects, including: Fast/slow/irregular heartbeat, seizures, weakness, loss of appetite, back/bone/joint/muscle pain, constipation, dry moutheye pain/redness/sensitivity to light, headache, nausea/vomiting, drowsiness, stomach/abdominal pain, increased thirst, …

What is secondary parathyroid disease?

secondary hyperparathyroidism When the parathyroid glands swell and release too much PTH, resulting in elevated PTH levels in the blood. This occurs in people with kidney disease for several reasons: Higher blood phosphorus levels. Kidneys cannot make active vitamin D (needed to absorb calcium)

What is paricalcitol used for?

Paricalcitol is used for Treatment and prevention of hyperparathyroidism in patients with chronic kidney disease who is on dialysis. Hyperparathyroidism is caused by excessive production of parathyroid hormone (PTH) by the parathyroid glands located in the neck.

What is the brand name of paricalcitol?

Zampra (Paricalcitol) injection is a form of vitamin D used to prevent and treat secondary hyperparathyroidism associated with stage 5 chronic kidney disease.

Is calcitriol a vitamin D analog?

Calcitriol is a Natural topical vitamin D3 analogs Both short- and long-term studies have demonstrated efficacy and safety with minimal risk of side effects.

What class of drugs does zemplar belong to?

Zemplar belongs to a group of drugs called Vitamin D analogswhich helps regulate PTH levels and increases calcium in the body.

Is Doxercalciferol a hectorol?

Dogcalcidol, the active ingredient in Hectorol® (Dogcalcidol liquid-filled capsules), is a Synthetic Vitamin D2 Analogs It undergoes metabolic activation in the body to form lα,25-dihydroxyvitamin D2 (lα,25-(OH)2D2), a naturally occurring biologically active form of vitamin D2.

What can hyperparathyroidism cause?

Hyperparathyroidism is one or more of your parathyroid glands becoming overactive and releasing (secreting) too much parathyroid hormone (PTH). This can lead to increased levels of calcium in the blood, a condition called hypercalcemia.

Is paricalcitol vitamin D?

[Paricalcitol – a selective vitamin D receptor activator for secondary hyperparathyroidism in patients with chronic kidney disease]

Is the parathyroid gland a hormone?

this parathyroid glands produces parathyroid hormone. This hormone helps maintain the proper balance of calcium in the blood and tissues that depend on calcium for normal function.

Can Auryxia cause constipation?

Adverse reactions. Advise patients that Auryxia may cause stool discoloration (dark color), but this stool staining is considered normal in iron-containing oral medications.Aurisha may cause diarrheanausea, constipation, vomiting, hyperkalemia, abdominal pain and cough.

Is there a generic for paricalcitol?

Paricalcitol (Zampra) is available as a generic drug, which can be much cheaper than the branded version.

What is another name for Zemplar?

Zemplar Capsules (Paricalcitol) is a man-made form of vitamin D used to treat hyperparathyroidism (overactive parathyroid glands) in people with chronic renal failure.

Is ergocalciferol a steroid?

Ergocalciferol is Steroids formed by photochemical bond cleavage of steroids, specifically, through the action of ultraviolet light (UV-B or UV-C) on ergosterol, a form of vitamin D2. Like cholecalciferol, ergocalciferol itself is inactive.

Is sertraline an antidepressant?

Sertraline is an antidepressant called selective serotonin reuptake inhibitor (SSRI). It is commonly used to treat depression, and sometimes panic disorder, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).

What are calcimimetic drugs?

Calcimimetic is a group of drugs Allosteric activators of calcium-sensing receptors, thereby enhancing signaling and reducing vitamin D-independent PTH release. The only commercially available calcimimetic is cinacalcet hydrochloride.

What is the prescription for torasemide?

Tosemide is used alone or in combination with other drugs to treat hypertension. Torsemide is used to treat edema (fluid retention; excess fluid in body tissues) caused by a variety of medical problems, including heart, kidney, or liver disease.

What happens if hyperparathyroidism is not treated?

If left untreated, the effects of hyperparathyroidism can lead to other health problems. In addition to kidney stones and osteoporosis, older patients may experience physical symptoms including depression, mood changes, fatigue, musclesas well as bone pain and pain, and even cardiac arrhythmias.

What are the 3 types of hyperparathyroidism?

There are three types of hyperparathyroidism: Primary, Secondary and Tertiary.

Is Secondary Hyperparathyroidism Chronic?

When calcium levels are low, parathyroid hormone is produced to try to raise blood calcium levels to normal levels. Chronic hypocalcemia leading to prolonged hyperparathyroidism secretion It’s called secondary hyperparathyroidism.