Phyllocontin Continus 225mg and Phyllocontin Forte Continus 350mg extended-release tablets (aminophylline) are discontinued for the treatment and prevention of bronchospasm in asthma and COPD.

Why was Phyllocontin discontinued?

They have discontinued Phyllocontin® Continus 225mg and Phyllocontin® Forte Continus 350mg Extended Release Tablets by business decision. Aminophylline is a mixture of theophylline and ethylenediamine, which easily releases theophylline in the body.

What does Phyllocontin 225 mg tablet do?

These pills are used to treat Asthma, chronic breathing difficulties such as chronic obstructive pulmonary disease and chronic bronchitis, sometimes used to treat heart failure in adults. They contain the active ingredient aminophylline, which belongs to a group of drugs called bronchodilators.

Is theophylline the same as aminophylline?

Aminophylline is an ethylenediamine salt Theophylline. Theophylline stimulates the central nervous system, skeletal and cardiac muscles. It relaxes certain smooth muscles in the bronchi, produces a diuresis, and causes increased gastric secretions. Aminophylline is the ethylenediamine salt of theophylline.

What are the side effects of Uniphyllin?

Patients treated with these tablets have reported the following side effects:

• feel nauseous.
• Headache.
• Vomiting (being sick), abdominal pain, diarrhea, heartburn, or a gastrointestinal disorder (such as an upset stomach).
• Difficulty falling asleep, agitation, anxiety, or shaking.
• Fast, slow, or irregular heartbeat.

3DS has been discontinued

29 related questions found

Is theophylline a steroid?

it’s not steroids« Theophylline relaxes the smooth muscles in the airways, making them open and allowing air to pass through them more easily, » says Dr Andy Whittamore, an in-house GP at the British Asthma Society. When you take theophylline at home, it usually lasts throughout the day in tablet or capsule form.

Are people still using theophylline?

Theophylline is Still one of the most widely prescribed medications for asthma and COPD Lung disease (COPD) as it is cheap and widely available.

What should I check before taking aminophylline?

Ask your pharmacist if you do not know if your medicine is an extended-release preparation.If this happens to you, call your doctor right away Nausea, vomiting, insomnia, irritability, seizures, increased heart rate, or headache. These can be signs of too much aminophylline in the blood.

Where is theophylline found?

Theophylline is present in Black tea with a small amount of green coffee, cocoa cotyledons and dried yerba mate. Theophylline is synthesized on an industrial scale and is mainly used in pharmaceutical preparations.

What is the common name for aminophylline?

Theophylline It is available under different brand names: Theo 24, Theochron, Elixophyllin, Aminophylline and Uniphyl.

What is replacing Phyllocontin?

Patients currently taking Phyllocontin will need to switch Monotheophylline If Methylxanthine is still deemed necessary.

What is theophylline?

This drug belongs to a class called Xanthine. It works by relaxing the muscles around the airways so they open up and you can breathe more easily. It also reduces the lung’s response to irritants. Controlling symptoms of breathing problems can reduce time lost to work or school.

Can Uniphyllin be halved?

Uniphyllin Continus tablets are designed to work properly within 12 hours. If the tablet is broken, crushed or chewed, the entire 12-hour dose may be quickly absorbed by your body. This can be dangerous and can cause serious problems, such as overdose.

When to prescribe montelukast?

About Montelukast

when is usually specified Asthma is mild and can stop it from getting worse. It can also help people with asthma who experience breathing difficulties during exercise (exercise-induced asthma) and seasonal allergies such as sneezing, itching, and a stuffy or runny nose (allergic rhinitis).

How to convert IV aminophylline to oral theophylline?

If changing from IV aminophylline to oral theophylline, the total daily dose of IV aminophylline should be multiplied by 0.8. or, Multiply the hourly aminophylline dose by 10to get the theophylline dose given every 12 hours.

When should theophylline levels be taken?

therapeutic drug monitoring

Measuring Plasma Theophylline Concentrations 5 days after initiation of oral therapy and at least 3 days after any dose adjustment. Blood samples should typically be collected 4-6 hours after oral extended-release formulations (sampling times may vary – see local guidelines).

Is it okay to drink coffee with theophylline?

theophylline caffeine

Avoid caffeinated beverages or foods, such as coffee, tea, cola and chocolate. If you use both medicines at the same time, you may need a dose adjustment or special tests.

Does green tea have theophylline?

Green tea extract contains PolyphenolsThese include the most active type, epigallocatechin gallate. Green tea and oolong tea have the highest polyphenol content. … other important components of tea include caffeine, theobromine, and theophylline.

Can you overdose on theophylline?

Data from this cohort study suggest that theophylline is a highly toxic drug that, when taken in overdose, May cause injury or death. There are three distinct modes of intoxication, namely acute intoxication, chronic overdose and acute treatment intoxication.

What are the common side effects of aminophylline?

The most common adverse events with peak serum theophylline below 20 mcg/mL were transient caffeine-like events such as Nausea, vomiting, headache and insomnia.

Why should we give aminophylline slowly?

Intravenous aminophylline must be administered very slowly Prevents dangerous central nervous system and cardiovascular side effects due to the direct stimulating effect of aminophylline.

What does calcium gluconate do for the heart?

Rapid injection of calcium gluconate may cause Vasodilation lowers blood pressurebradycardia, arrhythmias, syncope, and cardiac arrest.

Is theophylline still used for COPD?

For more than 70 years, theophylline has been used to treat chronic obstructive airway disease, including chronic obstructive pulmonary disease (COPD). It is still widely used around the worldbecause it is not expensive.

Is theophylline good for COPD?

Theophylline has been used as Bronchodilator It has been in the treatment of COPD for over 70 years, but has fallen out of favor due to the introduction of better tolerated and more effective bronchodilators.

Does coffee contain methylxanthine?

Methylxanthine, i.e. caffeine, theobromine and theophylline are present in a variety of beverages and foods, such as coffee, cocoa, tea and cola beverages. These substances can provide benefits to humans, but have also proven to be harmful primarily when consumed in large amounts.